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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register.
Register: ClinicalTrials.gov
Last refreshed on: 12 December 2020
Main ID:  NCT04071639
Date of registration: 26/08/2019
Prospective Registration: Yes
Primary sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University
Public title: Symptomatic Therapy for Patients With Huntington's Disease
Scientific title: Randomized Clinical Trial to Evaluate the Efficacy and Safety of Symptomatic Drug Therapy for Mild to Moderate Huntington's Disease Patients
Date of first enrolment: October 20, 2019
Target sample size: 100
Recruitment status: Recruiting
URL:  https://clinicaltrials.gov/show/NCT04071639
Study type:  Interventional
Study design:  Allocation: Randomized. Intervention model: Single Group Assignment. Primary purpose: Treatment. Masking: None (Open Label).  
Phase:  Phase 1
Countries of recruitment
China
Contacts
Name:     Zhi-Ying Wu, MD&PhD
Address: 
Telephone: +86-571-87783569
Email: zhiyingwu@zju.edu.cn
Affiliation: 
Key inclusion & exclusion criteria

Inclusion Criteria:

1. Genetic diagnosis of Huntington's disease

2. Symptomatic patients with Huntington's disease

3. Disease duration less than 5 years -

Exclusion Criteria:

(1) Movement disorder due to other definite causes instead of Huntington's disease (2)
Severe Lung, kidney or liver disease (3) Neoplastic Disease

-



Age minimum: N/A
Age maximum: N/A
Gender: All
Health Condition(s) or Problem(s) studied
Huntington Disease
Intervention(s)
Drug: Coenzyme Q10
Drug: Haloperidol
Drug: Risperidone
Drug: Zoloft
Primary Outcome(s)
The Unified Huntington's Disease Rating Scale [Time Frame: Five years]
Secondary Outcome(s)
Brain MRI [Time Frame: Five years]
Secondary ID(s)
2019238
Source(s) of Monetary Support
Please refer to primary and secondary sponsors
Secondary Sponsor(s)
Ethics review
Results
Results available:
Date Posted:
Date Completed:
URL:
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