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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register.
Last refreshed on: 12 December 2020
Main ID:  NCT04071639
Date of registration: 26/08/2019
Prospective Registration: Yes
Primary sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University
Public title: Symptomatic Therapy for Patients With Huntington's Disease
Scientific title: Randomized Clinical Trial to Evaluate the Efficacy and Safety of Symptomatic Drug Therapy for Mild to Moderate Huntington's Disease Patients
Date of first enrolment: October 20, 2019
Target sample size: 100
Recruitment status: Recruiting
Study type:  Interventional
Study design:  Allocation: Randomized. Intervention model: Single Group Assignment. Primary purpose: Treatment. Masking: None (Open Label).  
Phase:  Phase 1
Countries of recruitment
Name:     Zhi-Ying Wu, MD&PhD
Telephone: +86-571-87783569
Key inclusion & exclusion criteria

Inclusion Criteria:

1. Genetic diagnosis of Huntington's disease

2. Symptomatic patients with Huntington's disease

3. Disease duration less than 5 years -

Exclusion Criteria:

(1) Movement disorder due to other definite causes instead of Huntington's disease (2)
Severe Lung, kidney or liver disease (3) Neoplastic Disease


Age minimum: N/A
Age maximum: N/A
Gender: All
Health Condition(s) or Problem(s) studied
Huntington Disease
Drug: Coenzyme Q10
Drug: Haloperidol
Drug: Risperidone
Drug: Zoloft
Primary Outcome(s)
The Unified Huntington's Disease Rating Scale [Time Frame: Five years]
Secondary Outcome(s)
Brain MRI [Time Frame: Five years]
Secondary ID(s)
Source(s) of Monetary Support
Please refer to primary and secondary sponsors
Secondary Sponsor(s)
Ethics review
Results available:
Date Posted:
Date Completed:
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