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Note: This record shows only 22 elements of the WHO Trial Registration Data Set. To view changes that have been made to the source record, or for additional information about this trial, click on the URL below to go to the source record in the primary register.
Register: ClinicalTrials.gov
Last refreshed on: 19 February 2015
Main ID:  NCT00006054
Date of registration: 05/07/2000
Prospective Registration: Yes
Primary sponsor: Fairview University Medical Center
Public title: Allogeneic Bone Marrow Transplantation in Patients With Primary Immunodeficiencies
Scientific title:
Date of first enrolment: March 2000
Target sample size:
Recruitment status: Terminated
URL:  http://clinicaltrials.gov/show/NCT00006054
Study type:  Interventional
Study design:  Primary Purpose: Treatment  
Phase:  N/A
Countries of recruitment
United States
Contacts
Name:     K. Scott Baker
Address: 
Telephone:
Email:
Affiliation:  Fairview University Medical Center
Key inclusion & exclusion criteria

- Severe combined immunodeficiency All ages with histocompatible sibling donors or with
other donors OR Wiskott Aldrich syndrome All ages with histocompatible sibling donors
or with other donors OR X-linked CD40 ligand deficiency All ages with histocompatible
sibling donors OR Under 5 years of age with donors other than histocompatible
siblings OR Other primary immunodeficiencies without manifestations of
hemophagocytosis All ages with histocompatible sibling donors or with other donors OR
Hemophagocytic lymphohistiocytosis (HLH) Familial erythrophagocytic
lymphohistiocytosis (FEL), familial HLH (FHLH), recurrent virus-associated
hemophagocytic syndrome (VAHS) All ages with related or unrelated donors OR Chediak
Higashi syndrome All ages with related or unrelated donors OR X-linked
lymphoproliferative syndrome All ages with related or unrelated donors OR Other
primary immunodeficiencies with complication of hemophagocytosis All ages with
related or unrelated donors OR Severe progressive Langerhans cell histiocytosis All
ages with related or unrelated donors



Age minimum: N/A
Age maximum: 35 Years
Gender: Both
Health Condition(s) or Problem(s) studied
Chediak-Higashi Syndrome
Chronic Granulomatous Disease
Common Variable Immunodeficiency
Familial Erythrophagocytic Lymphohistiocytosis
Graft Versus Host Disease
Hemophagocytic Lymphohistiocytosis
Immunologic Deficiency Syndromes
Leukocyte Adhesion Deficiency Syndrome
Severe Combined Immunodeficiency
Virus-Associated Hemophagocytic Syndrome
Wiskott-Aldrich Syndrome
X-linked Agammaglobulinemia
X-linked Hyper IgM Syndrome
X-Linked Lymphoproliferative Syndrome
Intervention(s)
Drug: anti-thymocyte globulin
Drug: busulfan
Drug: cyclophosphamide
Drug: cyclosporine
Drug: etoposide
Drug: methotrexate
Drug: methylprednisolone
Drug: prednisone
Procedure: Allogeneic Bone Marrow Transplantation
Primary Outcome(s)
Secondary Outcome(s)
Secondary ID(s)
199/15104
UMN-MT-1995-26
UMN-MT-9526
Source(s) of Monetary Support
Please refer to primary and secondary sponsors
Secondary Sponsor(s)
Ethics review
Results
Results available:
Date Posted:
Date Completed:
URL:
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